The impact of the COVID-19 pandemic on the mental health of the population (literature review)
Authors
M.V. Ogar
“Medical Academy named after S.I. Georgievsky”; Federal State Autonomous Educational Institution of Higher Education “V.I. Vernadsky Crimean Federal University”, Simferopol, Republic of Crimea, Russian Federation
V.A. Verbenko
“Medical Academy named after S.I. Georgievsky”; Federal State Autonomous Educational Institution of Higher Education “V.I. Vernadsky Crimean Federal University”, Simferopol, Republic of Crimea, Russian Federation
https://doi.org/10.26617/1810-3111-2025-1(126)-75-87
Journal: Siberian Herald of Psychiatry and Addiction Psychiatry. 2025; 1 (126): 75-87.
Abstract
Background. The COVID-19 pandemic has had a significant impact on the mental health of the population, causing widespread depressive and anxiety disorders, especially among vulnerable groups. In the context of long-term social distancing, economic instability and increased stress, there is a need to study the psychiatric consequences of the pandemic, and this is especially important for the development of support measures for health workers, patients with mental disorders and people exposed to social isolation. This explains the demand for a systematic analysis of the mental health consequences of COVID-19 and effective methods for their correction. Objective: to review the published literature on the impact of the COVID-19 pandemic on the mental health of patients, their relatives, and medical staff. Material and Methods. The study of original research over the past 5 years from domestic and foreign scientific databases, selected by keywords: pandemic, mental health, psychological stress, anxiety, quarantine. Results and Discussion. Psychiatric symptoms of coronavirus disease include anxiety, depression, insomnia, chronic fatigue syndrome, post-traumatic stress disorder, obsessive-compulsive symptoms. Long-term self-isolation during the COVID-19 pandemic negatively affects the psychological health of the population, leading to the formation of post-viral fatigue syndrome, difficulty concentrating, daytime sleepiness, which together complicates a rapid recovery from the disease and a full return to professional duties. At the same time, young age and a history of psychological trauma increase the risk of psychological health disorders during the pandemic. Healthcare workers experienced high levels of anxiety and stress due to long shifts, the risk of infection, a lack of personal protective equipment and insufficient study of the new virus at the beginning of the pandemic. Conclusion. Patients with COVID-19 are subject to significant psychological stress after infection and may experience symptoms of post-traumatic stress disorder, comorbid depression, anxiety, and sleep disturbances. Patients who have recovered from COVID-19 continue to suffer from lingering symptoms such as chronic fatigue, diffuse myalgia, shortness of breath, headache, and difficulty concentrating, which significantly reduce their quality of life.
Keywords: pandemic, mental health, psychological stress, anxiety, lockdown.
Contacts
This email address is being protected from spambots. You need JavaScript enabled to view it.
Materials
For citation: Ogar M.V., Verbenko V.A. The impact of the COVID-19 pandemic on the mental health of the population (literature review). Siberian Herald of Psychiatry and Addiction Psychiatry2025; 1 (126): 75-87. https://doi.org/10.26617/1810-3111-2025-1(126)-75-87
REFERENCES
- Afari N, Ahumada SM, Wright LJ, Mostoufi S, Golnari G, Reis V, Cuneo JG. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis. Psychosom Med. 2014 Jan;76(1):2-11 https://doi.org/10.1097/PSY.0000000000000010. Epub 2013 Dec 12 PMID: 24336429; PMCID: PMC3894419.
- Mansueto G, Ruggiero GM, Palmieri S. The relationship between COVID-19 fear, affective symptoms and well-being: The mediating role of psychological flexibility. J Rat-Emo Cognitive Behav Ther. 2024;42:945-963. https://doi.org/10.1007/s10942-024-00556-z.
- Nalbandian A, Sehgal K, Gupta A et al. Post-acute COVID-19 syndrome. Nat Med. 2021 Apr;27(4):601-615. https://doi.org/10.1038/s41591-021-01283-z. Epub 2021 Mar 22.PMID: 33753937; PMCID: PMC8893149.
- Arnold DT, Hamilton FW, Milne A et al. Patient outcomes after hospitalization with COVID-19 and implications for follow-up: results from a prospective UK cohort. Thorax. 2021 Apr;76(4):399-401. https://doi.org/10.1136/thoraxjnl-2020-216086. Epub 2020 Dec 3. PMID: 33273026; PMCID: PMC7716340.
- Moreno-Pérez O, Merino E, Leon-Ramirez JM et al. Post-acute COVID-19 syndrome Incidence and risk factors: A Mediterranean cohort study. J Infect. 2021 Mar; 82(3):378-383. https://doi.org/10.1016/j.jinf.2021.01.004. Epub 2021 Jan 12. PMID: 33450302; PMCID: PMC7802523.
- Petrova NN, Pashkovsky VE, Sivashova MS, Gvozdetsky AN, Prokopovich GA. The influence of mental disorders on the outcome of COVID-19. Neurology, Neuropsychiatry, Psychosomatics.2021; 13(5):40-47(in Russian).
- Privalova MA, Sokolova MG, Kabanov MYu, Zueva ON, Bozhkov IA, Lopatina EV, Polyakov YuI. Retrospective analysis of cerebral neurological complications against the background of seasonal respiratory viral infections and the new coronavirus infection COVID-19. Medical Alphabet.2021;36:47-51.https://doi.org/10.33667/2078-5631-2021-36-47-51(in Russian).
- Rogers JP, Chesney E, Oliver D, Pollak TA, McGuire P, Fusar-Poli P, Zandi MS, Lewis G, David AS. Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic. Lancet Psychiatry. 2020 Jul;7(7):611-627. https://doi.org/10.1016/S2215-0366(20)30203-0. Epub 2020 May 18. PMID: 32437679; PMCID: PMC7234781.
- Tomasoni D, Bai F, Castoldi R, Barbanotti D, Falcinella C, Mulè G, Mondatore D, Tavelli A, Vegni E, Marchetti G, d'Arminio Monforte A. Anxiety and depression symptoms after virological clearance of COVID-19: A cross-sectional study in Milan, Italy. J Med Virol. 2021 Feb; 93(2):1175-1179. https://doi.org/10.1002/jmv.26459. Epub 2020 Sep 30. PMID: 32841387; PMCID: PMC7461061.
- Liu S, Yang L, Zhang C, Xiang YT, Liu Z, Hu S, Zhang B. Online mental health services in China during the COVID-19 outbreak. Lancet Psychiatry. 2020 Apr;7(4):e17-e18. https://doi.org/10.1016/S2215-0366(20)30077-8. Epub 2020 Feb 19. PMID: 32085841; PMCID: PMC7129099.
- Mazza M, Attanasio M, Pino MC, Masedu F, Tiberti S, Sarlo M, Valenti M. Moral decision-making, stress, and social cognition in frontline workers vs. population groups during the COVID-19 pandemic: An explorative study. Front Psychol. 2020 Nov 19;11:588159. https://doi.org/10.3389/fpsyg.2020.588159. PMID: 33329249; PMCID: PMC7710972.
- Petrova NN. Neuropsychiatric consequences of COVID-19. Juvenis Scientia. 2022;8(4):5-14 https://doi.org/10.32415/jscientia_2022_8_4_5-14 (in Russian).
- Carfì A, Bernabei R, Landi F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605. https://doi.org/10.1001/jama.2020.12603. PMID: 32644129; PMCID: PMC7349096.
- Poyraz BÇ, Poyraz CA, Olgun Y, Gürel Ö, Alkan S, Özdemir YE, Balkan İİ, Karaali R. Psychiatric morbidity and protracted symptoms after COVID-19. Psychiatry Res. 2021 Jan;295:113604. https://doi.org/10.1016/j.psychres.2020.113604. Epub 2020 Nov 28. PMID: 33296818; PMCID: PMC7695976.
- Townsend L, Dyer AH, Jones K et al Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection. PLoS One. 2020 Nov 9;15(11):e0240784. https://doi.org/10.1371/journal.pone.0240784. PMID: 33166287; PMCID: PMC7652254.
- Dashkin ER, Malysheva NA, Tsitselsky AA. Mental disorders associated with COVID-19. Medicine. Sociology. Philosophy. Applied research. 2021;2:36-41. https://doi.org/10.24411/2686-9365-2021-00003(in Russian).
- Shmatova YuE. Psychological state of residents of the Vologda region during the COVID-19 pandemic. Social Space. 2021;7(3).https://doi.org/10.15838/sa.2021.3.30.2 (in Russian).
- Jose C, Rudroff T, Chamard-Witkowski L. Editorial: The NeuroCOVID-19 syndrome: cognitive and psychological profiles, physiopathology, and impact on neurologically vulnerable populations. Front Neurol. 2024 Jul 19;15:1452895. https://doi.org/10.3389/fneur.2024.1452895. PMID: 39099780; PMCID: PMC11295108.
- Bai CJ, Ji DH, Chen LX, Li L, Wang CX. Reliability and validity of Insomnia Severity Index in clinical insomnia patients. Chin J Prac Nurs. 2018;34(28):2182-2186.
- Bansal AS, Bradley AS, Bishop KN, Kiani-Alikhan S, Ford B. Chronic fatigue syndrome, the immune system and viral infection. Brain Behav Immun. 2012 Jan; 26(1):24-31. https://doi.org/10.1016/j.bbi.2011.06.016. Epub 2011 Jul 2. PMID: 21756995.
- Azoulay E, Cariou A, Bruneel F et al. Symptoms of anxiety, depression, and peritraumatic dissociation in critical care clinicians managing patients with COVID-19. A cross-sectional study. Am J Respir Crit Care Med. 2020 Nov 15;202(10):1388-1398. https://doi.org/10.1164/rccm.202006-2568OC. PMID: 32866409; PMCID: PMC7667906.
- Andalib S, Biller J, Di Napoli M et al. Peripheral nervous system manifestations associated with COVID-19. Curr Neurol Neurosci Rep. 2021 Feb 14;21(3):9. https://doi.org/10.1007/s11910-021-01102-5. PMID: 33586020; PMCID: PMC7882462.
- Asadi-Pooya AA, Simani L. Central nervous system manifestations of COVID-19: A systematic review. J Neurol Sci. 2020 Jun 15;413:116832. https://doi.org/10.1016/j.jns.2020.116832. Epub 2020 Apr 11. PMID: 32299017; PMCID: PMC7151535.
- Sakamoto JS, Lopes-Santos LE, Lacerda KJCC, Trevisan AC, Alexandre-Santos L, Fukumori OY, Bellissimo-Rodrigues F, Wichert-Ana L. Changes in cerebral glucose metabolism among mild long COVID patients: an [18F]FDG PET/CT study. Braz J Med Biol Res. 2024 Nov 25;57:e14228. https://doi.org/10.1590/1414-431x2024e14228. PMID: 39607208; PMCID: PMC11653495.
- Guedj E, Campion JY, Dudouet P et al. 18F-FDG brain PET hypometabolism in patients with long COVID. Eur J Nucl Med Mol Imaging. 2021 Aug;48(9):2823-2833. https://doi.org/10.1007/s00259-021-05215-4. Epub 2021 Jan 26. PMID: 33501506; PMCID: PMC7837643.
- Campbell M, Varley-Campbell J, Fulford J, Taylor B, Mileva KN, Bowtell JL. Effect of immobilisation on neuromuscular function in vivo in humans: A systematic review. Sports Med. 2019 Jun;49(6):931-950. https://doi.org/10.1007/s40279-019-01088-8. Erratum in: Sports Med. 2019 Jun;49(6):981-986. https://doi.org/10.1007/s40279-019-01100-1. PMID: 30900205; PMCID: PMC6548068.
- Brooks SK, Webster RK, Smith LE, Woodland L, Wessely S, Greenberg N, Rubin GJ. The psychological impact of quarantine and how to reduce it: Rapid review of the evidence. Lancet.2020;395(10227):912-920.https://doi.org/10.1016/S0140-6736(20)30460-8.
- Beyerstedt S, Casaro EB, Rangel ÉB. COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection. Eur J Clin Microbiol Infect Dis. 2021 May;40(5):905-919. https://doi.org/10.1007/s10096-020-04138-6. Epub 2021 Jan 3. PMID: 33389262; PMCID: PMC7778857.
- Sergeeva VA, Lipatova TE. Sarcopenia associated with COVID-19. Preventive Medicine. 2022;25(11):105-112. https://doi.org/10.17116/profmed202225111105(in Russian).
- Alway SE, Myers MJ, Mohamed JS. Regulation of satellite cell function in sarcopenia. Front Aging Neurosci. 2014 Sep 22;6:246. https://doi.org/10.3389/fnagi.2014.00246. PMID: 25295003; PMCID: PMC4170136.
- Santos A, Magro DO, Evangelista-Poderoso R, Saad MJA. Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implications. Diabetol Metab Syndr. 2021 Mar 1;13(1):23. https://doi.org/10.1186/s13098-021-00639-2. PMID: 33648564; PMCID: PMC7919999.
- Chen S, Yang J, Yang W, Wang C, Bärnighausen T. COVID-19 control in China during mass population movements at New Year. Lancet. 2020 Mar 7;395(10226):764-766. https://doi.org/10.1016/S0140-6736(20)30421-9. Epub 2020 Feb 24. PMID: 32105609; PMCID: PMC7159085.
- Chen X, Laurent S, Onur OA, Kleineberg NN, Fink GR, Schweitzer F, Warnke C. A systematic review of neurological symptoms and complications of COVID-19. J Neurol. 2021 Feb;268(2):392-402. https://doi.org/10.1007/s00415-020-10067-3. Epub 2020 Jul 20. PMID: 32691236; PMCID: PMC7370630.
- Mohammadzadeh S, Mehrakizadeh A, Safari S, Mirzaaghayan M, Badkoubeh RS, Tavoosi A, Sardari A, Mohammadzadeh S, Larti F, Veldtman GR. Lessons learnt from COVID-19 in adult congenital heart patient in Tehran: a survey-based study of prevention, exposure, susceptibility, and outcomes. Cardiol Young. 2021 Apr;31(4):617-626. https://doi.org/10.1017/S1047951120004400. Epub 2020 Nov 18. PMID: 33203486; PMCID: PMC7844187.
- Bao Y, Sun Y, Meng S, Shi J, Lu L. 2019-nCoV epidemic: address mental health care to empower society. Lancet. 2020 Feb 22;395(10224):e37-e38. https://doi.org/10.1016/S0140-6736(20)30309-3. Epub 2020 Feb 7. PMID: 32043982; PMCID: PMC7133594.
- Shi L, Lu ZA, Que JY, Huang XL, Liu L, Ran MS, Gong YM, Yuan K, Yan W, Sun YK, Shi J, Bao YP, Lu L. Prevalence of and risk factors associated with mental health symptoms among the general population in China during the coronavirus disease 2019 pandemic. JAMA Netw Open. 2020 Jul 1;3(7):e2014053. https://doi.org/10.1001/jamanetworkopen.2020.14053. PMID: 32609353; PMCID: PMC7330717
- Holmes EA, O'Connor RC, Perry VH et al. Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science. Lancet Psychiatry. 2020 Jun;7(6):547-560. https://doi.org/10.1016/S2215-0366(20)30168-1. Epub 2020 Apr 15. PMID: 32304649; PMCID: PMC7159850.
- Bromet EJ, Atwoli L, Kawakami N et al. Post-traumatic stress disorder associated with natural and human-made disasters in the World Mental Health Surveys. Psychol Med. 2017 Jan;47(2):227-241. https://doi.org/10.1017/S0033291716002026. Epub 2016 Aug 30. PMID: 27573281; PMCID: PMC5432967.
- Chertovikova AS. Psychotraumatic factors in conditions of isolation. Problems of Modern Pedagogical Education. 2018;60-1:485-489 (in Russian).
- Shepeleva II, Chernysheva AA, Kiryanova EM, Salnikova LI, Gurina OI. COVID-19: damage to the nervous system and psychological and psychiatric complications. Social and Clinical Psychiatry.2020;30(4):76-82 (in Russian).
- Preti E, Di Mattei V, Perego G, Ferrari F, Mazzetti M, Taranto P, Di Pierro R, Madeddu F, Calati R. The Psychological Impact of Epidemic and Pandemic Outbreaks on Healthcare Workers: Rapid Review of the Evidence. Curr Psychiatry Rep. 2020 Jul 10;22(8):43. https://doi.org/10.1007/s11920-020-01166-z. PMID: 32651717; PMCID: PMC7350408.
- Abdullaev AM, Mosolov OA, Ivanova LK. Study of burnout syndrome in health care workers amid the COVID-19 pandemic. Bulletin of the Medical Institute “REAVIZ”. Rehabilitation, Doctor and Health. 2021;(6):13-20. https://doi.org/10.20340/vmi-rvz.2021.6.COVID.2(in Russian).
- Sun P, Wang M, Song T, Wu Y, Luo J, Chen L, Yan L. The psychological impact of COVID-19 pandemic on health care workers: A systematic review and meta-analysis. Front Psychol. 2021 Jul 8;12:626547. https://doi.org/10.3389/fpsyg.2021.626547. PMID: 34305703; PMCID: PMC8297953.
- Korekhova MV, Novikova IA, Solovyev AG, Kirov MYu. Features of the mental state of doctors of various specialties during the COVID-19 pandemic. Russian Journal of Preventive Medicine. 2023;26(3):81‑90. https://doi.org/10.17116/profmed20232603181(in Russian).
- Bell C, Williman J, Beaglehole B, Stanley J, Jenkins M, Gendall P, Rapsey C, Every-Palmer S. Challenges facing essential workers: a cross-sectional survey of the subjective mental health and well-being of New Zealand healthcare and 'other' essential workers during the COVID-19 lockdown. BMJ Open. 2021 Jul 19;11(7):e048107. https://doi.org/10.1136/bmjopen-2020-048107. PMID: 34281926; PMCID: PMC8290948.
- Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res. 2002 Feb;52(2):69-77. https://doi.org/10.1016/s0022-3999(01)00296-3. PMID: 11832252.
- Bocéréan C, Dupret E. A validation study of the Hospital Anxiety and Depression Scale (HADS) in a large sample of French employees. BMC Psychiatry. 2014 Dec 16;14:354. https://doi.org/10.1186/s12888-014-0354-0. PMID: 25511175; PMCID: PMC4476305.
- Chigwedere OC, Sadath A, Kabir Z, Arensman E. The impact of epidemics and pandemics on the mental health of healthcare workers: A systematic review. Int J Environ Res Public Health. 2021 Jun 22;18(13):6695. https://doi.org/10.3390/ijerph18136695. PMID: 34206264; PMCID: PMC8296866.
- Sareen J, Erickson J, Medved MI, Asmundson GJ, Enns MW, Stein M, Leslie W, Doupe M, Logsetty S. Risk factors for post-injury mental health problems. Depress Anxiety. 2013 Apr;30(4):321-7. https://doi.org/10.1002/da.22077. Epub 2013 Feb 13. PMID: 23408506.
- Sinbukhova EV, Protsenko DN. Assessment of the psychological state of medical personnel during the COVID-19 pandemic. Anesthesiology and Resuscitation. 2020;6-2:54-60. https://doi.org/10.17116/anaesthesiology202006254 (in Russian).
- Bagcchi S. Stigma during the COVID-19 pandemic. Lancet Infect Dis. 2020 Jul;20(7):782. https://doi.org/10.1016/S1473-3099(20)30498-9. PMID: 32592670; PMCID: PMC7314449.
- Bachilo EV, Barylnik YuB, Shuldyakov AA, Efremov AA, Novikov DE. Mental health of health workers during the COVID-19 pandemic in Russia: results of a cross-sectional online survey. Psychiatry and Psychopharmacotherapy. 2020;22(3):49-55 (in Russian).
- Wang C, Pan R, Wan X, Tan Y, Xu L, McIntyre RS, Choo FN, Tran B, Ho R, Sharma VK, Ho C. A longitudinal study on the mental health of general population during the COVID-19 epidemic in China. Brain Behav Immun. 2020 Jul;87:40-48. https://doi.org/10.1016/j.bbi.2020.04.028. Epub 2020 Apr 13. PMID: 32298802; PMCID: PMC7153528.
- Tomlin J, Dalgleish-Warburton B, Lamph G. Psychosocial support for healthcare workers during the COVID-19 pandemic. Front Psychol. 2020 Aug 11;11:1960. https://doi.org/10.3389/fpsyg.2020.01960. PMID: 32849149; PMCID: PMC7431467.
- Bass C, Gardner WN. Respiratory and psychiatric abnormalities in chronic symptomatic hyperventilation. Br Med J (Clin Res Ed). 1985 May 11;290(6479):1387-90. https://doi.org/10.1136/bmj.290.6479.1387. PMID: 3922504; PMCID: PMC1415586.
- UstinovaNV, KarkashadzeGA, Namazova-BaranovaLS. Cognitive, emotional, and behavioral disorders in children with respiratory allergic diseases: causes and solutions. Pediatric Pharmacology. 2024;21(3):226-239. https://doi.org/10.15690/pf.v21i3.2757(in Russian).